DropPet® AT2 is a high-purity (≥95.0%) anti-aging peptide ingredient centered on Acetyl Tetrapeptide-2, supplied as a white to off-white powder. Known as a "topical lifting peptide," it utilizes a unique biomimetic mechanism to precisely target the Dermal-Epidermal Junction (DEJ), promoting the synthesis of Laminin-5 and Collagen VII to reinforce the skin's "foundation." This ingredient effectively combats laxity and sagging, enhances contour firmness, and serves as an ideal core ingredient for developing premium lifting serums, firming creams, and anti-aging ampoules.
상호 :
DropPet® AT2INCI 이름 :
Acetyl Tetrapeptide-2CAS 번호 :
757942-88-4모습 :
White to off-white powder분석(HPLC) :
≥95.0%패키지 :
CustomizableAs we age, the connection between the dermis and epidermis (DEJ) gradually flattens or even breaks down, which is one of the root causes of contour laxity, sagging, and deepening wrinkles. The ingredient utilizes cutting-edge biomimetic technology to mimic natural human protein fragments. It not only stimulates the production of key basement membrane proteins, acting like "rivets" to re-anchor the connection between the dermis and epidermis, but also promotes dermal matrix reconstruction, supporting the three-dimensional contour from the inside out and restoring youthful firmness.
Lifting & Firming Serums · Contour Creams · Anti-Aging Repair Ampoules · Eye Lifting Creams · Leave-on Anti-Aging Formulas
The core targets of Acetyl Tetrapeptide-2 are Laminin-5 and Collagen VII, which are the essential "rivets" forming the basement membrane (DEJ). This peptide significantly increases their expression, allowing the previously flattened and lax dermal-epidermal junction to regain its tightly interlocking "wave-like" structure. This structural reinforcement effectively prevents the epidermis from sliding downward under the influence of gravity, achieving a visibly firming and lifting effect.
In addition to reinforcing the basement membrane, DropPet® AT2 sends youthful signals to fibroblasts, stimulating the synthesis of Type I collagen and elastin. This helps replenish the lost support structures in the dermis, increasing skin thickness and density, improving structural aging issues such as nasolabial folds and marionette lines, and restoring a plump and abundant appearance to the skin.
This ingredient has excellent water solubility. It is recommended to add it during the aqueous phase, after cooling to below 40℃. Operationally, slowly add the white powder into deionized water or an aqueous phase containing glycols (such as butylene glycol) under stirring, and stir thoroughly until completely clear and dissolved before proceeding with subsequent emulsification or thickening steps. To maintain maximum bioactivity, avoid prolonged high-temperature heating. The recommended use level is 0.05%–0.5% (based on the final formulation).
They operate at different levels. Acetyl Hexapeptide-8 (botox-like) targets the muscle layer to address "dynamic wrinkles"; Palmitoyl Pentapeptide-4 targets the dermis to address "static wrinkles caused by collagen loss"; while Acetyl Tetrapeptide-2 in DropPet® AT2 targets the dermal-epidermal junction (DEJ) to address "laxity and sagging caused by foundation collapse." It is ideally suited to be paired with hexapeptides and pentapeptides to form a three-dimensional anti-aging matrix of "muscle-dermis-basement membrane."
Natural skin metabolism and basement membrane reconstruction take time. It is generally recommended to use continuously for over 28 days (a complete skin metabolic cycle) to initially perceive improvements in skin firmness and elasticity; for noticeably sagging areas, continuous use for 8–12 weeks is recommended for significant improvement. To achieve optimal results, it is suggested to pair it with antioxidants (like Vitamin C, Ferulic Acid) and adequate basic hydration in the formula, while reminding consumers to practice daily photoprotection.
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