DropBrigt® Litein – The Next-Generation Brightening & Anti-Aging Active

Unlock Cellular Beauty with DropBrigt^® Litein
In the quest for radiant, youthful skin, the key lies not just in surface-level treatments, but in empowering the skin’s own defense and renewal mechanisms. Introducing DropBrigt^® Litein (INCI: Oxothiazolidinecarboxylic Acid, CAS 19771-63-2) — a groundbreaking active that works at the cellular level to promote brighter, smoother, and more resilient skin.

🌟 How Does DropBrigt^® Litein Work?

DropBrigt^® Litein is a precursor to glutathione, the body’s master antioxidant. Unlike topical glutathione, which has limited absorption, Litein effectively penetrates skin cells and stimulates the natural synthesis of glutathione, enhancing the skin’s intrinsic ability to:

• Inhibit Tyrosinase Activity – Reducing melanin production and shifting synthesis from dark eumelanin to lighter phaeomelanin.

• Neutralize Free Radicals – Protecting proteins, lipids, and DNA from oxidative damage.

• Repair UV-Induced Damage – Lowering ROS and lipid peroxidation for stronger anti-photoaging benefits.

📊 Clinically Proven Efficacy

1. Powerful Antioxidant & Anti-Melanogenic Action

• ↓ ROS by 28.8% at 0.1% concentration after UVB exposure (p < 0.001)

• ↓ MDA (lipid peroxidation) by 54.84% at 0.1% (p < 0.001)

• Boosts intracellular glutathione, shifting melanin type and brightening skin tone

2. Strengthens Skin Under Stress

In muscle fatigue studies, cells treated with Litein showed better stress resilience, maintaining performance under prolonged exertion — a promising model for skin under environmental or emotional stress.

3. Safe & Non-Toxic

• IC₅₀ = 5.66 mg/mL (3T3 fibroblast assay)

• Oral LD₅₀ > 2630 mg/kg – Classified as non-toxic (GHS Category 5)

• Non-irritating, non-comedogenic, and suitable for sensitive skin

🧴 Formulation Advantages

• Water-soluble, compatible with a wide pH range

• Stable under normal processing conditions – no special stabilizers required

• Synergistic with antioxidants like sodium sulfite, sodium metabisulfite, and vitamin C

• Versatile applications: serums, creams, ampoules, and brightening treatments

✅ Recommended Use

🧪 Quality Specifications

💡 Why Choose DropBrigt^® Litein?

Whether you’re developing a brightening serum, anti-aging cream, or photoprotective formula, DropBrigt^® Litein offers:

• Dual brightening & anti-aging benefits

• Cellular-level activation of glutathione

• Clinically validated antioxidant performance

• Excellent safety and formulation flexibility

Formulate with Confidence. Formulate with Science.
Integrate DropBrigt^® Litein into your next skincare innovation and deliver visible, lasting radiance.

If you are interested in our products and want to know more details, please contact judyzhou@drop-bio.com.